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BBMRI-LPC Biobanks









1958BC - Cohorts of Great Britain

Short description of background, aims, hosting institution:

The 1958 Birth Cohort (The National Child Development Study) includes individuals who were born in Britain in one week in March 1958. Information about their lives was gathered at birth and ages 7, 11, 16, 23, 33, 42, 45, 46 and 50 years. Additionally, immigrants born at the same time were recruited to the cohort and followed from 7, 11 or 16 years onward.

In 2001 the MRC (MRC Centre of Epidemiology for Child Health) funded the collection of biomedical data from the cohort. This had not been collected since the participants were 16. This project took seven years to complete, and succeeded in gathering biomedical data from more than 9,000 individuals from the cohort from 2002 to 2004 when they were 44-45 years old. It included the testing and measurement of:

  • height and sitting height
  • weight
  • waist and hips
  • blood pressure
  • lung function
  • vision
  • hearing

and the collection of biosamples.

All available data can be accessed through the UK Data Service at the University of Essex. Access to data from the Biomedical Sweep can be obtained from the UK Data Archive under Special License. Access to biological samples and linkage of genotype phenotype data is through the Access Committee for CLS Cohorts.


Main focus of research:

Physical and educational development, economic circumstances, employment, family life, health behavior, wellbeing, social participation attitudes as well as health related areas including obesity, Type 2 diabetes, vitamin D and related traits, myopia/ hyperopia.


Approximate number of probands:

17,000 probands


Types and number of biosamples available:

saliva, blood: ca. 8.000 samples,
DNA samples: 8018 of which 7526 have been transformed into immortalized cell cultures.


Contact:

Centre for Longitudinal Studies
Institute of Education
University of London
20 Bedford Way,
London, WC1H 0AL
Tel: +44 (0)20 7612 6875


Contact for BBMRI-LPC:

Paul Burton
Professor of Genetic Epidemiology
Department of Health Sciences
University of Leicester
Adrian Building, University Road
Leicester, LE1 7RH
Tel: ++44 116 252 5992
Email: cohort1958[at]le.ac.uk


Further information:

For further information click here.

Baseline variables: www.cls.ioe.ac.uk/datadictionary/page.asp?section=000100010001
&sectionTitle=National+Child+Development+Study+%281958+Cohort%29






BBMRI-LPC Biobanks
c/o Technische Universität München • Institute for Medical Statistics and Epidemiology • Ismaninger Str. 22 • D-81675 München
tel: +49 (0)89-3187-4066 & +49 (0)89-4140-4320 • wichmann[at]helmholtz-muenchen.de & klaus.kuhn[at]lrz.tu-muenchen.de
Last modification of this page: 09.02.2015
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