GAZEL - Cohorts of France
Short description of background, aims, hosting institution:
The GAZEL Cohort Study was set up in 1989 among Électricité de France-Gaz de France (EDF-GDF) workers. It is an open epidemiologic laboratory characterized by a broad coverage of health problems and determinants and accessible to the community of researchers. At inception in 1989, the GAZEL Cohort Study included volunteers working at EDF-GDF then aged from 35 to 50 years The cohort is broadly diverse in terms of social, economic, and occupational status, health, and health-related behavior. The data collected routinely cover diverse dimensions and come from different sources: annual self-administered questionnaire (morbidity, lifestyles, life events, etc.); personnel department of EDF-GDF for social, demographic, and occupational characteristics; EDF-GDF Special Social Insurance fund (for sickness absences and cancer and ischemic heart disease registries), occupational medicine (occupational exposure and working conditions), Social Action Fund (healthcare utilization), Health Screening Centers for standardized health examination and the constitution of a biobank, and the National Death Register (causes of death). Follow-up has been excellent, and the number of subjects lost to follow-up was exceptionally low; active participation by the self-administered questionnaire is also elevated.
GAZEL is administerd by INSERM (Institut national de la santé et de la recherche médicale).
Main focus of research:
Determinants of health status and disease.
Approximate number of probands:
20.000 (15.011 men and 5.614 women), 8.000 probands with biosamples.
Types and number of biosamples available:
DNA, serum, plasma; ca. 380,000 samples.
Pr Marcel Goldberg
Dr Marie Zins
Plate-forme de recherche - Cohortes en population
U 1018 Inserm
Hopital Paul Brousse
16 avenue Paul Vaillant Couturier
94807 VILLEJUIF CEDEX
Phone: (+33) 01 77 74 74 26
Contact for BBMRI-LPC:
Marie Zins, Annette Leclerc, Marcel Goldberg. The French GAZEL Cohort Study: 20 years of epidemiologic research. Advances in Life Course Research, Volume 14, Issue 4, December 2009, Pages 135-146, ISSN 1040-2608