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BBMRI-LPC Biobanks

Twin registry - Cohorts of Sweden

Short description of background, aims, hosting institution:

The Swedish Twin Registry was established in the 1960s by the Karolinska Institute to study how smoking affects our health.

The Swedish Twin Registry (STR) today contains more than 194,000 twins and more than 75,000 pairs have zygosity determined by an intra-pair similarity algorithm, DNA, or by being of opposite sex. Of these, approximately 20,000, 25,000, and 30,000 pairs are monozygotic, same-sex dizygotic, and opposite-sex dizygotic pairs, respectively. Since its establishment, the STR has been an important epidemiological resource for the study of genetic and environmental influences on a multitude of traits, behaviors, and diseases. Following large investments in the collection of biological specimens in the past 10 years we have now established a Swedish twin biobank, which effectively has also transformed the registry into a powerful resource for molecular studies.

There are currently about 30 ongoing projects based on the Swedish twin registry.

Main focus of research: wide range of public health issues with a focus on dementia diseases, allergies, cancer and cardiovascular diseases.

Approximate number of probands: 200,000; 45,000 with biosamples.

Types and number of biosamples available: serum, whole blood, DNA; ca. 130,000 samples.


Swedish Twin Registry
Fax: +46 (0)831 4975
E-mail: tvillingregistret[at]

Mailing address:

Swedish Twin Registry
Department of Medical Epidemiology and Biostatistics
Karolinska Institutet
PO Box 281
SE-171 77 Stockholm

Contact for BBMRI-LPC:

Nancy Pedersen
Department of Medical Epidemiology and Biostatistics
Karolinska Institutet

Further information:

Website: The Swedish Twin Registry

BBMRI-LPC Biobanks
c/o Technische Universität München • Institute for Medical Statistics and Epidemiology • Ismaninger Str. 22 • D-81675 München
tel: +49 (0)89-3187-4066 & +49 (0)89-4140-4320 • wichmann[at] & klaus.kuhn[at]
Last modification of this page: 09.02.2015